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Singulair (Montelukast) Buyer and Patient Handbook in Singapore

Singulair (Montelukast) is a leukotriene-receptor antagonist indicated for the treatment of Asthma and the relief of Allergic Rhinitis symptoms. It belongs to the class of leukotriene modifiers and is available as a small oral tablet.

What is Singulair?

Singulair is a tablet that blocks leukotrienes-chemicals released during an allergic response that cause airway narrowing and inflammation. It is approved by the Health Sciences Authority (HSA) of Singapore for:

• Asthma control (including exercise-induced bronchoconstriction)
• Allergic rhinitis (seasonal and perennial)
• Prevention of chronic airway inflammation

The drug is marketed worldwide under the brand name Singulair, while the generic name is montelukast.

Who Should Use Singulair?

• Adults and adolescents (12 years +) with persistent asthma who need additional control beyond inhaled corticosteroids.
• Children 5 - 11 years for asthma or allergic rhinitis (dose adjusted by weight).
• Individuals who experience exercise-induced bronchospasm.
• Patients who prefer an oral tablet over inhaler therapy for mild-to-moderate symptoms.

How Does It Work?

Montelukast binds to cysteinyl-leukotriene-1 (CysLT₁) receptors on airway smooth muscle and inflammatory cells, preventing leukotrienes from triggering bronchoconstriction and mucus production. Think of it as installing a “stop-sign” at the traffic lights that normally let inflammation rush through. By dampening this pathway, the medication reduces wheezing, coughing, and nasal congestion.

Safety note: Montelukast has a low potential for abuse and is not a controlled substance.

Why Choose Singulair?

• Convenient oral dosing eliminates the need for inhaler technique training.
• Proven efficacy in both asthma control and seasonal allergy relief, supported by extensive clinical data.
• Generic availability (montelukast tablets) offers a cost-effective alternative with identical bio-equivalence.

Off-label uses-such as treating certain dermatologic conditions-should only be considered after professional advice.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

How to Take

• Take once daily in the evening for asthma; morning dosing is acceptable for allergic rhinitis.
• Swallow the tablet whole with a glass of water; food does not affect absorption.
• If you miss a dose, take it as soon as you remember unless it is near the time of the next scheduled dose-then skip the missed tablet and continue with the regular schedule.

Missed Dose

• Do not double-dose. Taking two tablets at once can increase the risk of side effects.

Overdose

• If an overdose is suspected, seek immediate medical attention or contact Singapore’s National Poison Centre (180-225 5555). Typical symptoms include severe headache, Drowsiness, or Nausea.

Special Populations

• Elderly: No dosage adjustment required; monitor for neuropsychiatric changes.
• Renal/hepatic impairment: No routine dose change, but monitor clinical response.
• Pregnancy & lactation: Category B; generally considered safe, but discuss with a healthcare professional.

Lifestyle & Diet

• Grapefruit juice does not interact with montelukast.
• Alcohol does not affect efficacy, but excessive intake may worsen asthma symptoms.
• Maintain regular exercise; singulair is effective for preventing exercise-induced bronchospasm when taken at least 2 hours before activity.

Precautions and Warnings

• Neuropsychiatric effects: Mood changes, Depression, or suicidal thoughts have been reported; report any new psychological symptoms promptly.
• Allergic reactions: Rash, angioedema, or Anaphylaxis require urgent medical care.
• Hepatic dysfunction: Rare liver enzyme elevations-monitor if pre-existing liver disease exists.

Drug Interactions

Only a few clinically significant interactions are known; always inform your healthcare provider of all medicines you take.

Potential Side Effects

Common Side Effects

• Headache
• Stomach Pain or indigestion
• Cough
• Nasal congestion

Less Common Side Effects

• Dizziness
• Fatigue
• Muscle aches

Serious Side Effects

• Mood alterations (depression, Anxiety, aggression) - seek help immediately.
• Allergic reactions (hives, swelling, difficulty breathing) - emergency care required.
• Liver enzyme elevation - monitor if symptoms of hepatitis appear (jaundice, dark urine).

Who Should Avoid This Medication?

• Known hypersensitivity to montelukast or any tablet excipients.
• Patients who have experienced severe neuropsychiatric reactions to montelukast previously.

Storage Instructions

• Keep tablets in the original container tightly closed.
• Store at room temperature (15-30 °C), away from direct sunlight and moisture.
• Keep out of reach of children; dispose of unused tablets responsibly.

Singulair Alternatives

Frequently Asked Questions

How quickly does Singulair start working for asthma?

It begins to reduce airway inflammation within a few hours, but full effect may take several days of regular use. Consistency is essential for optimal control.

Can I use Singulair with my inhaled rescue inhaler?

Yes, Singulair is meant to be an add-on controller and does not replace a short-acting bronchodilator for acute symptoms.

Is Singulair safe for people with hypertension?

There is no direct interaction; however, any new medication should be discussed with a clinician if you have cardiovascular concerns.

Will Singulair cure my allergies?

No, it alleviates symptoms by blocking leukotrienes but does not eliminate the underlying allergic response. Continued avoidance of triggers remains important.

Does Singulair interact with common cold medicines?

Most over-the-counter cold remedies are safe, but avoid combining with drugs that strongly induce liver enzymes (e.g., certain antifungals).

Can I take Singulair while pregnant?

Montelukast is classified as Category B in Singapore, indicating no proven risk in animal studies; however, discuss any medication use with your obstetrician.

What should I do if I forget to take my dose for several days?

Resume the regular once-daily schedule; no loading dose is required. Monitor asthma control and contact a healthcare professional if symptoms worsen.

Are there any foods I must avoid while on Singulair?

There are no specific dietary restrictions, but maintaining a balanced diet supports overall respiratory health.

How long can I stay on Singulair?

It can be used long-term as part of an asthma or allergy management plan, provided regular clinical review confirms continued benefit.

Is a blood test required before starting Singulair?

Routine testing is not mandatory, but baseline liver function may be checked in patients with pre-existing liver disease.

Glossary

• Leukotriene: Inflammatory chemicals that cause airway narrowing and mucus production.
• CysLT₁ receptor: The primary site where leukotrienes act to trigger asthma symptoms.
• Bio-equivalent: Two products that have the same rate and extent of absorption, delivering identical therapeutic effect.

Disclaimer

The information provided here is for general educational purposes only. It does not constitute medical advice, and off-label uses should be discussed with a qualified health professional. Our online pharmacy supplies only legally approved medicines; users are responsible for ensuring suitability and for following local regulations. Always consult a doctor or pharmacist before starting, changing, or stopping any medication.