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Generic Solifenacin Buyer and Patient Handbook in Singapore

What is Solifenacin?

Solifenacin is a prescription-only antimuscarinic medication used to treat symptoms of an overactive bladder, such as urgency, frequency, and urge incontinence. It belongs to the class of bladder antispasmodics and is approved by the Health Sciences Authority (HSA) in Singapore. The drug is supplied as an oral tablet (pill).

Who Should Use Solifenacin?

• Adults diagnosed with overactive bladder symptoms.
• Individuals whose symptoms are not adequately controlled by lifestyle measures alone.
• Patients who can safely take anticholinergic agents (no severe Glaucoma, urinary retention, or uncontrolled narrow-angle glaucoma).

How Does It Work?

Solifenacin blocks muscarinic M3 receptors in the bladder wall, reducing involuntary muscle contractions that cause urgency. Think of it as turning down the "engine" that drives sudden bladder spasms, allowing more controlled emptying. It does not affect the heart or blood pressure, so cardiovascular safety is generally good.

Why Choose Solifenacin?

• Efficacy: Clinical trials show consistent reduction in daily urgency episodes.
• Convenient dosing: Once-daily tablet simplifies adherence.
• Availability: Both brand (Vesicare) and generic versions are on the Singapore market, offering cost-saving options.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

Dose is taken once daily, preferably at the same time each day.

How to Take

• Swallow the tablet whole with a full glass of water.
• Can be taken with or without food; consistency helps maintain stable blood levels.

Missed Dose

• If you remember within 12 hours, take it immediately.
• If more than 12 hours have passed, skip the missed dose and resume your regular schedule.

Overdose

• Seek emergency medical care promptly.
• Provide the name “Solifenacin” and the amount taken to healthcare professionals.

Special Populations

• Elderly: Start at 5 mg; monitor for dry mouth and constipation.
• Renal impairment: Dose may need reduction; consult a pharmacist.
• Hepatic impairment: Use with caution; avoid if severe.

Lifestyle & Diet

• Drink plenty of fluids (except when fluid restriction is advised).
• Limit caffeine and alcohol as they can irritate the bladder.
• Avoid grapefruit juice, which may increase solifenacin levels.

Precautions and Warnings

• May cause dry mouth, constipation, and blurred vision; stay hydrated and maintain a high-fiber diet.
• Use caution if you have narrow-angle glaucoma or urinary retention.
• Inform your pharmacist of any history of severe kidney or liver disease.

Drug Interactions

Potential Side Effects

Common Side Effects

• Dry mouth
• Constipation
• Blurred vision

Less Common Side Effects

• Dizziness
• Nausea
• Urinary retention

Serious Side Effects

• Severe allergic reaction (rash, swelling, breathing difficulty) - seek immediate medical help.
• Acute urinary retention - contact a healthcare professional urgently.

Who Should Avoid This Medication?

• Patients with uncontrolled narrow-angle glaucoma.
• Individuals with urinary retention not caused by overactive bladder.
• Those with known hypersensitivity to solifenacin or any tablet excipients.

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at 20-25 °C (68-77 °F); protect from excess heat and moisture.
• Keep out of reach of children and pets.

Solifenacin Alternatives

Frequently Asked Questions

How long does it take to feel an improvement?

Most patients notice a reduction in urgency episodes within 1-2 weeks, with full benefit often reached after 4-6 weeks.

Can I take Solifenacin with my blood pressure medication?

Generally yes, but inform your pharmacist of all current medicines to rule out specific interactions.

Is it safe to drink coffee while on Solifenacin?

Caffeine can irritate the bladder and may lessen the drug’s benefit; limit intake if you notice worsening symptoms.

What should I do if I experience severe constipation?

Increase dietary fiber, hydrate well, and consider a mild laxative after consulting a pharmacist.

Can Solifenacin be used for children?

It is approved for adults only; pediatric use is not recommended.

Does alcohol affect Solifenacin?

Alcohol may increase bladder irritation and the risk of dizziness; moderate consumption is advisable.

Will I need regular blood tests while taking Solifenacin?

Routine renal or hepatic function tests are recommended for patients with known organ impairment, but not for everyone.

What is the difference between the 5 mg and 10 mg tablets?

The 10 mg tablet delivers a higher dose and may provide stronger symptom control, but it also carries a slightly higher risk of side effects.

Glossary

• Antimuscarinic: A drug that blocks muscarinic receptors, reducing bladder muscle activity.
• Overactive bladder: A condition marked by sudden urges to urinate, frequent urination, and possible leakage.
• CYP3A4: An enzyme in the liver that metabolizes many medications; inhibitors can raise drug levels.

Disclaimer

This handbook provides general information about Solifenacin and is not a substitute for professional medical advice. Off-label uses are not discussed; any such consideration should involve a qualified health professional. Our service offers a convenient platform to purchase medicines through licensed Singapore pharmacies; users remain responsible for ensuring the medication is appropriate for their condition. Always consult a healthcare provider before starting, stopping, or changing any medication.