Esidrix

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esidrix

$33.60

Generic Esidrix (Hydrochlorothiazide) 12.5mg and 25mg tablets are available to purchase from our Singapore pharmacy with reliable delivery. This thiazide diuretic works by increasing urine production to reduce excess fluid and lower blood pressure effectively. Esidrix helps manage hypertension, heart failure, and edema by promoting sodium and water excretion through the kidneys. It is an ideal solution for adults managing high blood pressure or fluid retention who require effective diuretic therapy for cardiovascular health.

Table of contents

Esidrix (Hydrochlorothiazide) Buyer and Patient Handbook in Singapore

Esidrix (Hydrochlorothiazide) is a thiazide-type diuretic prescribed to help lower blood pressure and reduce fluid retention. It belongs to the class of diuretics and is commonly used for Hypertension and mild Edema. The product is approved by the Health Sciences Authority (HSA) of Singapore and is available in pill form.

What is Esidrix?

Esidrix contains the active ingredient hydrochlorothiazide, a thiazide diuretic that promotes the excretion of sodium and water through the kidneys. It is indicated for the management of essential hypertension and for reducing swelling caused by Heart Failure, liver disease, or kidney disorders. The medication is supplied as oral tablets in strengths of 12.5 mg and 25 mg.

Who Should Use Esidrix?

  • Adults diagnosed with High Blood Pressure (systolic ≥ 140 mm Hg or diastolic ≥ 90 mm Hg).
  • Patients with mild to moderate peripheral edema not caused by acute kidney injury.
  • Individuals who have been evaluated by a qualified healthcare professional and deemed appropriate for thiazide therapy.

How Does It Work?

Hydrochlorothiazide blocks the sodium-chloride transporter in the distal convoluted tubule of the kidney, reducing sodium reabsorption. The resulting loss of sodium pulls water out of the bloodstream, lowering blood volume and consequently decreasing blood pressure. This fluid-shifting effect is comparable to turning down the water pressure in a garden hose, which eases the strain on the heart.

Why Choose Esidrix?

  • Established efficacy: Long-standing evidence supports its ability to lower blood pressure and reduce fluid overload.
  • Convenient dosing: Once-daily tablets simplify adherence compared with multiple-dose regimens.
  • Cost-effective: Generic hydrochlorothiazide tablets are widely available, offering a cheaper alternative with equivalent therapeutic outcomes.

Dosage, Administration, Lifestyle and Dietary Recommendations

  • 12.5 mg tablet: Typically started at one tablet once daily.
  • 25 mg tablet: May be prescribed if the lower dose does not achieve target blood pressure, taken once daily.

How to Take

  • Swallow the tablet whole with a full glass of water.
  • Can be taken with or without food; consistency daily improves effect.

Missed Dose

  • If you remember within 12 hours, take the missed tablet.
  • If it is later than 12 hours, skip it and resume the regular schedule; do not double-dose.

Overdose

  • Seek immediate medical attention if more than the prescribed amount is taken.
  • Symptoms may include extreme dizziness, rapid heartbeat, or severe dehydration.

Special Populations

  • Elderly: Start at the lowest dose (12.5 mg) and monitor kidney function closely.
  • Renal impairment: Dose reduction may be necessary; avoid if creatinine clearance < 30 mL/min without specialist advice.
  • Pregnancy & lactation: Use only if clearly needed; discuss risks with a healthcare professional.

Lifestyle & Diet

  • Limit high-salt foods (e.g., processed snacks, soy sauce) to enhance the drug’s effect.
  • Avoid excessive potassium-rich supplements unless advised, as the drug can raise potassium levels.
  • Stay hydrated but do not over-drink fluids; aim for balanced intake throughout the day.

Precautions and Warnings

  • Monitor blood pressure regularly; too low readings (< 90/60 mm Hg) may cause dizziness.
  • Check electrolyte levels (especially potassium and sodium) at baseline and during therapy.
  • Use caution if you have a history of Gout, as thiazides can increase uric acid levels.
  • Inform your clinician about any liver disease, Diabetes, or thyroid disorders.

Drug Interactions

Drug Class Interaction Risk Recommended Action
NSAIDs (e.g., ibuprofen) Reduces diuretic effect Use lowest effective NSAID dose; monitor BP
ACE inhibitors / ARBs Additive blood-pressure lowering May be beneficial; watch for hyper-kalemia
Lithium Increases lithium levels Avoid concomitant use; if necessary, monitor lithium serum levels

Potential Side Effects

Common Side Effects

  • Increased urination
  • Light-headedness or dizziness
  • Mild muscle cramps

Less Common Side Effects

Serious Side Effects

  • Severe dehydration or electrolyte imbalance → seek medical help promptly.
  • Allergic reaction (rash, swelling, breathing difficulty) → emergency care required.

Who Should Avoid This Medication?

  • Individuals with known hypersensitivity to hydrochlorothiazide or any component of the tablet.
  • Patients with anuria (no urine output) or severe kidney failure.
  • Those with a history of sulfonamide allergy, as cross-reactivity may occur.

Storage Instructions

  • Keep tablets in the original container, tightly closed.
  • Store at room temperature (15 °C-30 °C), away from moisture and direct sunlight.
  • Keep out of reach of children and pets.

Esidrix Alternatives

Name Class Key Difference
Hydrochlorothiazide (generic) Thiazide diuretic Same active ingredient, lower cost
Indapamide Thiazide-like diuretic Longer half-life, may be better for some patients
Losartan Angiotensin II receptor blocker Works via a different pathway; useful if thiazides not tolerated

Frequently Asked Questions

How soon will I notice a drop in blood pressure after starting Esidrix?

Most patients see a modest reduction within 2 weeks; full effect may take up to 4-6 weeks.

Can I take Esidrix on an empty stomach?

Yes, the tablet can be taken with or without food, but keep the timing consistent each day.

Will Esidrix affect my ability to exercise?

Initially you may feel more frequent urination; stay hydrated and avoid intense activity until you adapt.

Is it safe to drink alcohol while on Esidrix?

Moderate alcohol is generally acceptable, but excessive intake can worsen low blood pressure and dehydration.

Do I need to monitor my potassium levels?

Yes, periodic checks are recommended, especially if you are on other medications that affect potassium.

What should I do if I develop a rash?

Stop the medication and contact a healthcare professional promptly; a rash could signal an allergic reaction.

Can Esidrix be used for weight loss?

No. The medication is intended for blood-pressure control and fluid management, not for cosmetic weight loss.

How often should I have my blood pressure checked?

Initially weekly for the first month, then every 1-3 months once stable, or as advised by your clinician.

Glossary

  • Thiazide diuretic: A class of drugs that increase urine production by inhibiting sodium reabsorption in the kidneys.
  • Electrolyte: Minerals (e.g., potassium, sodium) essential for nerve and muscle function; balance is critical during diuretic therapy.
  • Gout: A form of arthritis caused by excess uric acid crystals in joints; certain diuretics can raise uric acid levels.

Disclaimer

The information provided here is for educational purposes only and does not replace professional medical advice. Off-label uses are not covered; always consult a qualified healthcare provider before starting, stopping, or altering any medication. Our service offers information and facilitates access to medicines through licensed Singaporean pharmacies; it does not prescribe or dispense drugs. Users are responsible for ensuring the suitability of any medication for their personal health condition.

Esidrix Properties

  • Original Manufacturer: Merck & Co.
  • Clinical use: Treatment of hypertension and edema
  • Spectrum of activity: Diuretic
  • Mechanism of action: Inhibits sodium reabsorption in the distal tubule
  • Classification: Thiazide diuretic
  • Recommended Dosage: 12.5-50 mg once daily
  • Basic Side Effects: Dizziness, Headache, Frequent urination
  • Moderate Side Effects: Hypokalemia, Hyperglycemia
  • Serious Side Effects: Severe electrolyte imbalance, Acute kidney injury

Esidrix Drug Class

Thiazide Diuretics

How to purchase Esidrix on our Website

To purchase Esidrix | Hydrochlorothiazide on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.

Esidrix / Hydrochlorothiazide pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Esidrix pills are dispatched from outside Singapore due to prescriptions issued overseas.

Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.

Reviews

4.75/187
Esidrix

Been on 12.5mg for 3 weeks now for my BP. Doctor insisted I try this before stronger stuff. First few days were rough - felt super dizzy if I stood up too fast. Main issue is the leg cramps at night. Woke up with a charley horse that nearly made me scream. Still, my numbers are down, so I guess it's working. Read on a forum to eat a banana a day for the cramps. Trying that now.

Mei L. Kuala Lumpur, Malaysia

Prescribed for mild swelling in my ankles. Only been a week. It definitely makes you pee. A lot. I take it at 7 AM and by 10 AM I've visited the toilet three times. The dry mouth is no joke either, I keep a water bottle glued to my hand. Taste of food is a bit off too. Not sure if the slight reduction in swelling is worth this hassle yet. Following advice to take it with food helped a bit with the nausea.

Arjun S. Bangkok, Thailand

Five years on 25mg. It controls my blood pressure like a champion. My biggest tip: take it first thing when you wake up, or you'll be up all night peeing. The trade-off is the sun sensitivity. I live in Singapore, and if I forget sunscreen for even 10 minutes, I get a rash. Also, you have to watch your electrolytes. I get blood tests yearly to check potassium. It's a maintenance thing, but it works.

Ahmed R. Singapore, Singapore

My doctor calls this a \"water pill\" and that's exactly what it does. On it for 2 years post-heart scare. The key is consistency. If you miss a dose, you can feel the fluid building up. My hack is to set a phone alarm and always have a stock. Side effect nobody tells you: it can mess with your gout. Had my first flare-up after starting this. Now I avoid purine-rich foods like sardines and liver, which I love. Small price to pay, I suppose.

Maria C. Manila, Philippines

Been taking Esidrix for hypertension for about 8 months. It does the job, but the fatigue is real sometimes. I split my 25mg pill in half and take 12.5mg in the morning and the other half after lunch. This \"hack\" I read about online prevents that mid-afternoon crash. Also, you MUST drink more water than you think you need, otherwise the muscle cramps are unbearable. It's a balancing act.

Wei J. Jakarta, Indonesia

Two-year user here. Works great for blood pressure, but it totally killed my ability to enjoy a cold beer. Even one beer dehydrates me so badly now, I feel awful the next day. Also, my skin gets ridiculously dry, especially in air-conditioned offices. I have to moisturize like crazy. Pro-tip from my doc: don't take it with coffee, it makes the dizziness worse. I wait at least an hour after my pill.

David T. Penang, Malaysia

Mixed bag. It helped a lot with the water retention from my other medication, which was the goal. But it pushed my blood sugar up. My doctor wasn't too surprised, said it can happen. So now I'm on a lower dose of Esidrix and also watching my sugar intake. It's frustrating when a solution creates another problem. The constant thirst is manageable, but the blood sugar thing is a new worry.

Siti A. Johor Bahru, Malaysia

Prescribed for high BP, but it's had a weird side effect on my mood. I feel more... flat? Not depressed, just less excited about things. My blood pressure is perfect though. I tried skipping a dose to see, and I did feel more \"alive,\" but my BP crept back up. It's a trade-off I'm not sure I'm happy with. Talking to my doc next week about alternatives. The physical side effects I can handle, but this is different.

Chandra W. Bali, Indonesia

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