Buy Contrave
contrave
$78.30
- Active ingredient: Bupropion Plus Naltraxone
- Category: Men's Health
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Contrave (Bupropion and Naltrexone 8/90mg) tablets are available to purchase from our trusted Singapore pharmacy with discreet delivery. This unique combination works by targeting areas of the brain involved in hunger control and reward processing, helping to reduce appetite and cravings. It is designed for adults seeking pharmacological support for chronic weight management alongside diet and exercise, offering a complementary approach to achieving weight loss goals.
Table of contents
- Contrave (Bupropion Plus Naltraxone) Buyer and Patient Handbook in Singapore
- What is Contrave?
- Who Should Use Contrave?
- How Does It Work?
- Why Choose Contrave?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Contrave Alternatives
- Frequently Asked Questions
- How long does it take to see weight loss with Contrave?
- Can I drink coffee while taking Contrave?
- Does Contrave affect blood sugar levels?
- I feel dizzy after the first few doses-what should I do?
- Is Contrave safe for people over 65?
- Can I use Contrave if I have mild liver disease?
- What should I do if I miss a dose for several days?
- Does Contrave interact with over-the-counter supplements?
- Will I regain the weight after stopping Contrave?
- How is Contrave supplied in Singapore?
- Glossary
- Disclaimer
- How to purchase Contrave on our Website
- Reviews
- Write your review
Contrave (Bupropion Plus Naltraxone) Buyer and Patient Handbook in Singapore
What is Contrave?
Contrave is a combination pill containing Bupropion and Naltrexone, approved for chronic weight management in adults with Obesity or overweight + weight-related comorbidities. It belongs to the class of centrally-acting appetite-suppressants. In Singapore, the product is regulated by HSA and carries the same safety standards as FDA-approved formulations. The tablet is available in a fixed-dose of 8 mg bupropion and 90 mg naltrexone.
Who Should Use Contrave?
- Adults ≥ 18 years with a body-mass index (BMI) ≥ 30 kg/m², or BMI ≥ 27 kg/m² with at least one obesity-related condition (e.g., Hypertension, dyslipidaemia, Type 2 Diabetes).
- Individuals who have not achieved sufficient weight loss through diet and exercise alone.
- Patients who can adhere to a structured lifestyle-modification programme alongside medication.
How Does It Work?
Contrave targets two brain pathways that influence eating behaviour. Bupropion stimulates pro-opiomelanocortin (POMC) neurons, which reduce appetite and increase energy expenditure. Naltrexone blocks an inhibitory feedback loop, enhancing the POMC signal. Think of it as releasing the brakes on a car’s accelerator while also giving the driver a slight “push” forward, resulting in decreased food intake and higher calorie burn. The formulation carries a low abuse potential, but patients with a history of seizure disorder should be cautious.
Why Choose Contrave?
- Dual-action: The combination provides greater weight-loss efficacy than either component alone.
- Evidence-based: Clinical trials demonstrate an average 5-10 % reduction in body weight after one year when paired with diet and exercise.
- Generic alternatives: Once available, generic versions may lower cost while delivering the same bioequivalence.
- Off-label use: Not recommended; any alternative indication should be discussed with a qualified health professional.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- Initiate with one tablet (8/90 mg) daily for the first week.
- Increase to one tablet twice daily (morning and evening) from week 2 onward, as tolerated.
- Do not exceed two tablets per day.
How to Take
- Swallow the tablet whole with a full glass of water.
- Take each dose with food to minimise gastrointestinal discomfort.
- Maintain a consistent schedule (e.g., breakfast and dinner) for steady drug levels.
Missed Dose
- If you miss a dose and it is less than 6 hours until the next scheduled dose, skip the missed tablet.
- Do not double-dose to “make up” for the missed one.
Overdose
- Common symptoms include Nausea, Vomiting, rapid heart rate, and Seizures.
- Seek immediate medical attention or contact the Singapore Poison Centre (180-274-6688).
Special Populations
- Elderly (≥ 65 years): Start at the lowest dose and monitor for dizziness or blood-pressure changes.
- Renal or hepatic impairment: Dose adjustment may be required; consult a healthcare provider.
- Pregnancy & lactation: Contraindicated; avoid use.
Lifestyle & Diet
- Avoid excessive alcohol, as it can increase seizure risk.
- Limit intake of high-calorie, low-nutrient foods; aim for a calorie deficit of 500-750 kcal/day.
- Regular physical activity (≥ 150 min moderate aerobic exercise per week) amplifies weight-loss results.
Precautions and Warnings
- Do not use if you have uncontrolled hypertension, a seizure disorder, or a history of eating-disorder-related bingeing.
- Monitor blood pressure and heart rate monthly during the first three months.
- Sudden discontinuation may lead to weight regain; taper under supervision if cessation is needed.
Drug Interactions
| Drug Class | Interaction Risk | Management |
|---|---|---|
| Monoamine oxidase inhibitors (MAOIs) | Severe hypertensive crisis | Discontinue MAOI ≥ 14 days before starting Contrave |
| CYP2B6 inhibitors (e.g., fluoxetine) | ↑ bupropion levels → seizures | Dose reduction or avoid |
| Opioid analgesics | Reduced naltrexone efficacy | Monitor pain control; consider alternative analgesics |
Potential Side Effects
Common Side Effects
- Nausea
- Headache
- Dry mouth
- Constipation
Less Common Side Effects
- Insomnia
- Dizziness
- Tremor
- Increased blood pressure
Serious Side Effects
- Seizures - stop immediately and seek emergency care.
- Severe allergic reaction (rash, swelling, difficulty breathing) - call emergency services.
- Persistent High Blood Pressure - contact a healthcare professional promptly.
Who Should Avoid This Medication?
- Individuals with a current or past diagnosis of an eating disorder (e.g., Bulimia, Anorexia).
- Patients with uncontrolled hypertension (≥ 160/100 mmHg).
- Those taking opioid therapy for Chronic Pain.
- Anyone allergic to bupropion, naltrexone, or any excipients in the tablet.
Storage Instructions
- Store at 20-25 °C (68-77 °F) in a dry place away from direct sunlight.
- Keep the bottle tightly closed to protect from moisture.
- Keep out of reach of children and pets.
Contrave Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Saxenda (liraglutide) | GLP-1 analogue | Injectable; higher weight-loss potential but requires daily injection |
| Orlistat | Lipase inhibitor | Works in the gut to reduce fat absorption; gastrointestinal side effects common |
| Phentermine + Topiramate | Sympathomimetic + anticonvulsant | Higher efficacy but increased cardiovascular and cognitive risks |
Frequently Asked Questions
How long does it take to see weight loss with Contrave?
Most users notice a modest reduction (≈ 2 kg) within the first 8 weeks, with continued loss up to 12 months when paired with diet and exercise.
Can I drink coffee while taking Contrave?
Yes, moderate caffeine intake (≤ 2 cups per day) is acceptable, but excessive caffeine may exacerbate insomnia.
Does Contrave affect blood sugar levels?
Bupropion can modestly improve glycaemic control, but regular monitoring is advised for patients with Diabetes.
I feel dizzy after the first few doses-what should I do?
Dizziness is a common early-stage effect; try taking the tablet with food and ensure adequate hydration. If symptoms persist beyond two weeks, seek medical advice.
Is Contrave safe for people over 65?
It can be used cautiously; start at one tablet daily and monitor blood pressure and mental status closely.
Can I use Contrave if I have mild liver disease?
Mild hepatic impairment usually does not require dose adjustment, but any liver condition warrants physician oversight.
What should I do if I miss a dose for several days?
Restart the titration schedule from the beginning (one tablet daily for a week) to minimise side-effects.
Does Contrave interact with over-the-counter supplements?
St. John’s wort and other serotonergic supplements may increase seizure risk; avoid them unless cleared by a healthcare professional.
Will I regain the weight after stopping Contrave?
Weight regain is common if lifestyle changes are not maintained; a gradual taper and continued diet/exercise can mitigate this.
How is Contrave supplied in Singapore?
It is available as a 30-tablet bottle of the fixed-dose 8 mg/90 mg formulation, dispensed by registered pharmacies.
Glossary
- BMI (Body-Mass Index): A ratio of weight (kg) to height squared (m²) used to classify obesity.
- POMC neurons: Brain cells that release peptides reducing appetite and increasing energy use.
- Bioequivalence: Pharmaceutical term indicating a generic drug has the same rate and extent of absorption as the brand product.
Disclaimer
The information provided here is for general educational purposes and reflects current knowledge about Contrave. It does not constitute medical advice, nor does it replace consultation with a qualified health professional. Off-label uses are not endorsed. Our platform offers access to licensed pharmacies; users remain responsible for ensuring the medication suits their health needs. Always discuss any concerns or potential interactions with a healthcare provider before starting or stopping any medication.
How to purchase Contrave on our Website
To purchase Contrave | Bupropion Plus Naltraxone on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Contrave / Bupropion-plus-naltraxone pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Contrave pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Started Contrave 3 weeks ago. The first few days were brutal with nausea and this weird metallic taste in my mouth that just wouldn't go away. But the cravings? They've definitely dulled. I don't feel like snacking all the time. My hack was to eat a small banana or some plain crackers before taking the pill. It made a huge difference. Still waiting to see if the scale moves.
Horrible headaches and felt jittery like I'd had ten cups of coffee. Only lasted two days. The insomnia was the killer. I was exhausted but just couldn't sleep. Called my pharmacist and he said it's common. Told me to switch to taking it right after breakfast instead of dinner. It's still early days, jury's out.
Been on it for 9 months, down 18 kilos. The key is water. I drink 3 liters a day, otherwise the constipation is real. I also learned to avoid coffee for at least two hours after my dose, cuts down the anxiety. It doesn't magically make you lose weight, but it makes saying 'no' to that second roti canai so much easier.
A year in. It's been a tool, not a cure. My appetite is just... quieter. But the dry mouth never fully went away for me. I always have sugar-free lozenges on hand. Biggest lesson: if you miss a dose, don't double up the next day. I did that once and felt dizzy all afternoon. Just take the next one as scheduled.
After 6 months, I realised the effect on appetite wears off a bit. My doctor suggested splitting my dose - half in the morning, half in the afternoon. This worked way better for me, felt more even throughout the day. Lost 12 kilos so far but it's a slow grind. The mental focus from the bupropion part is a nice bonus.
It stopped my binge eating, which was the main goal. For the first time, I can have a pack of biscuits in the house and not finish it in one sitting. The trade-off is I feel a bit flat emotionally sometimes. Not sad, just less joy. I try to combat it with evening walks. It's a strange trade, but for now, it's worth it.
My experience is mixed. It helped me quit smoking, which is amazing. But for weight loss? Nothing. If anything, I feel more snacky. The nausea at the start was awful, had to force myself to eat plain rice. So it's a win for smoking cessation, a bust for weight management in my case. Weird how it affects everyone differently.
Only took it for a month. The constant dry mouth and dizziness were too much. I felt anxious and couldn't concentrate at work. I know some people push through, but for me the side effects weren't worth the slight reduction in appetite. I'm trying diet changes alone now. Maybe it just wasn't for my body chemistry.