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Cobra-120 (Sildenafil) Buyer and Patient Handbook in Singapore

What is Cobra-120?

Cobra-120 is a sildenafil-containing oral tablet (120 mg) that belongs to the phosphodiesterase-5 (PDE-5) inhibitor class, used to improve erectile function. The medication is approved by the Health Sciences Authority (HSA) in Singapore for the treatment of Erectile Dysfunction (ED). It is supplied as a single-dose pill for oral administration.

Who Should Use Cobra-120?

• Men aged 18 years and older experiencing difficulty achieving or maintaining an erection.
• Individuals whose ED is caused by vascular, neurologic, or psychological factors.
• Patients who have tried lower-dose PDE-5 inhibitors without satisfactory results and have no contraindications to higher doses.

How Does It Work?

Cobra-120 blocks the enzyme PDE-5, which normally breaks down cyclic guanosine monophosphate (cGMP). By inhibiting PDE-5, cGMP accumulates in the smooth muscle of the penis, leading to relaxation of blood vessels and increased blood flow during sexual stimulation.

Impact: Think of it like a traffic light that turns green for blood to flow into the penile tissue, enabling a firmer erection when sexual arousal occurs.

Safety note: The 120 mg dose is considered high; it should only be taken after confirming tolerance to lower doses, as the risk of side effects rises with higher exposure.

Why Choose Cobra-120?

• Higher potency: The 120 mg strength may provide a stronger response for men who did not respond adequately to 50 mg or 100 mg tablets.
• Convenient single-dose form: No need for dose titration on the day of activity-just take one tablet as needed.
• Availability: Distributed through licensed pharmacies in Singapore, with generic alternatives offering cost savings.

Off-label use (e.g., Pulmonary Hypertension) should only be considered under professional medical supervision.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 120 mg taken once per sexual encounter.
• Do not exceed one tablet within a 24-hour period.

How to Take

1. Swallow the tablet whole with a glass of water.
2. Take it 30-60 minutes before anticipated sexual activity.
3. Sexual stimulation is required for the medication to work.

Missed Dose

• If you forget to take a dose and sexual activity is still planned within the next 2 hours, you may still take it.
• If more than 2 hours have passed, skip the missed dose and wait for the next planned occasion.

Overdose

• Seek immediate medical attention if you experience severe headache, vision changes, chest Pain, or prolonged erection lasting > 4 hours.

Special Populations

• Elderly (≥ 65 years): Start with a lower dose (e.g., 50 mg) to assess tolerance before moving to 120 mg.
• Renal or hepatic impairment: Use caution; dosage adjustment may be required.
• Children: Not approved for use.

Lifestyle & Diet

• Alcohol: Moderate intake is acceptable, but excessive drinking can reduce effectiveness and increase side-effects.
• Grapefruit: Avoid large quantities as it may increase sildenafil levels.
• Heavy meals: High-fat meals can delay onset; consider a lighter meal before dosing.

Precautions and Warnings

• Do not use if you have had a recent stroke, myocardial infarction, or uncontrolled hypertension.
• Avoid simultaneous use with nitrates (e.g., nitroglycerin) due to risk of severe hypotension.
• Document any history of retinal disorders (e.g., retinitis pigmentosa) as PDE-5 inhibitors may affect vision.
• Inform your healthcare provider if you are taking alpha-blockers, as combined use may cause low blood pressure.

Drug Interactions

Potential Side Effects

Common Side Effects

• Headache
• Flushing
• Nasal congestion
• Dyspepsia (indigestion)

Less Common Side Effects

• Dizziness
• Back Pain
• Visual disturbances (blurred vision, blue-tinted vision)

Serious Side Effects

• Priapism ( erection lasting > 4 hours) - seek emergency care
• Sudden hearing loss - consult a physician promptly
• Severe chest pain or palpitations - seek immediate medical attention

Who Should Avoid This Medication?

• Men using nitrate-containing medications.
• Individuals with severe uncontrolled hypertension (≥ 180/110 mmHg).
• Patients with a known hypersensitivity to sildenafil or any tablet excipients.
• Men with a history of non-arteritic anterior ischemic optic neuropathy (NAION).

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at room temperature (15-30 °C).
• Protect from moisture, light, and heat.
• Keep out of reach of children and pets.

Cobra-120 Alternatives

Frequently Asked Questions

How long does Cobra-120 stay effective?

Effect starts within 30-60 minutes and can last up to 4-6 hours, depending on individual response and dose.

Can I take Cobra-120 if I have high blood pressure?

If your blood pressure is well-controlled and you are not on nitrates, the medication can be used, but you should discuss any cardiovascular concerns with a qualified health professional first.

Is it safe to combine Cobra-120 with alcohol?

A modest amount of alcohol usually does not interfere, but excessive drinking may worsen side effects such as dizziness and headache.

What should I do if I experience a painful erection lasting longer than 4 hours?

Treat it as medical emergency - seek immediate care to prevent permanent tissue damage.

Can I take Cobra-120 on an empty stomach?

Yes, but high-fat meals can delay absorption, so a lighter meal may give faster results.

Are there any foods I should avoid?

Large quantities of grapefruit or grapefruit juice can increase drug levels and should be avoided.

Is it okay to use Cobra-120 more than once a week?

The medication can be used as often as once per day, but most men find 2-3 times per week sufficient for both efficacy and safety.

Does Cobra-120 improve libido?

It facilitates the physiological response (erection) but does not directly increase sexual desire.

Can I take Cobra-120 if I have mild liver disease?

Mild impairment may be tolerated, but dose adjustment may be necessary; consult a health professional before use.

Will Cobra-120 affect my vision permanently?

Temporary visual changes are possible, but permanent vision loss is rare; discontinue use and seek medical advice if you notice persistent visual disturbances.

Glossary

• Phosphodiesterase-5 (PDE-5) inhibitor: A drug that blocks the enzyme responsible for breaking down cGMP, enhancing blood flow to the penis.
• cGMP (cyclic guanosine monophosphate): A messenger molecule that relaxes smooth muscle, allowing blood to fill the erectile tissue.
• Priapism: A prolonged, often painful erection lasting more than four hours, requiring urgent treatment.

Disclaimer

The information provided here is for general educational purposes only and does not substitute professional medical advice. All medication use, including off-label applications, should be discussed with a qualified health professional. Our online pharmacy platform offers convenient access to licensed products, but the ultimate responsibility for safe use rests with the reader. Always follow local regulations and consult a doctor before starting any new medication.