Buy Kaletra
kaletra
$238.84
- Active ingredient: Lopinavir | Ritonavir
- Category: Antivirals
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Kaletra (Lopinavir/Ritonavir) 60-tablet bottles are available to order from our Singapore pharmacy with reliable delivery. This combination antiretroviral works by blocking HIV protease enzyme, preventing the virus from replicating and spreading in the body. Ritonavir boosts lopinavir levels for enhanced effectiveness against HIV strains. It is an essential treatment for adults living with HIV who require reliable viral suppression as part of their antiretroviral regimen.
Table of contents
- Kaletra (Lopinavir; Ritonavir) Buyer and Patient Handbook in Singapore
- What is Kaletra?
- Who Should Use Kaletra?
- How Does It Work?
- Why Choose Kaletra?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Kaletra Alternatives
- Frequently Asked Questions
- How long does it take for Kaletra to lower HIV viral load?
- Can I take Kaletra with coffee?
- What if I experience diarrhea?
- Is it safe to travel abroad while on Kaletra?
- Can Kaletra be taken during pregnancy?
- Does Kaletra interact with herbal supplements like St. John’s wort?
- What should I do if I miss two consecutive doses?
- Are there any dietary restrictions besides grapefruit?
- How often should liver function be tested?
- Can I switch from brand Kaletra to a generic version?
- Glossary
- Disclaimer
- Kaletra Properties
- Kaletra Connected Conditions
- How to purchase Kaletra on our Website
- Reviews
- Write your review
Kaletra (Lopinavir; Ritonavir) Buyer and Patient Handbook in Singapore
What is Kaletra?
Kaletra is a combination antiviral tablet containing the protease inhibitors lopinavir and ritonavir. It is used to treat HIV-1 infection in adults and adolescents. The product is FDA-approved and registered with Singapore’s Health Sciences Authority, supplied in a bottle of tablets.
Who Should Use Kaletra?
- Adults and adolescents (≥12 years) with confirmed HIV-1 infection.
- Patients who need a boosted protease-inhibitor regimen.
- Individuals who can swallow tablets and have no contraindicating drug interactions.
How Does It Work?
Kaletra blocks the HIV protease enzyme, preventing the virus from maturing into an infectious form. Ritonavir inhibits the metabolism of lopinavir, boosting its blood levels-much like a “fuel pump” that keeps the drug active longer. It does not cure HIV, but it suppresses viral replication when taken correctly.
Why Choose Kaletra?
- Proven efficacy as a fixed-dose combination in many clinical trials.
- Convenient twice-daily dosing reduces pill burden compared with separate agents.
- Generic versions are available, offering comparable antiviral activity at a lower cost.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- 2 tablets (60 mg/80 mg each) taken twice daily, preferably with food.
- One bottle contains 60 tablets, enough for 15 days of therapy at the standard dose.
How to Take
- Swallow tablets whole with a full glass of water.
- Take them with meals to improve absorption and reduce gastrointestinal upset.
Missed Dose
- If you realize a dose is missed within 12 hours, take it as soon as you remember.
- If it is near the time of the next scheduled dose, skip the missed one-do not double-dose.
Overdose
- Seek immediate medical attention or contact the Singapore Poison Centre.
- Symptoms may include Nausea, Vomiting, stomach Pain, or dizziness.
Special Populations
- Elderly: No dosage adjustment, but monitor renal and hepatic function.
- Children <12 years: Not recommended; pediatric formulations should be considered.
- Hepatic impairment: Use with caution; dose may need reduction in severe cases.
Lifestyle & Diet
- Avoid grapefruit or grapefruit juice as they can increase lopinavir levels.
- Alcohol does not interact directly, but excessive intake may worsen liver toxicity.
Precautions and Warnings
- Monitor liver enzymes regularly; hepatotoxicity can occur.
- Use effective contraception; Kaletra may reduce hormonal contraceptive efficacy.
- Report any new rash, especially if accompanied by fever or malaise, as it may signal a serious reaction.
Drug Interactions
| Drug Class | Risk | Action |
|---|---|---|
| CYP3A4 inducers (e.g., rifampicin) | Decreases lopinavir/ritonavir levels | Avoid co-administration or adjust dose |
| Anticoagulants (warfarin) | May increase INR | Monitor coagulation parameters |
| Anti-arrhythmics (e.g., amiodarone) | Increases plasma concentrations | Observe for toxicity, consider alternative |
Potential Side Effects
Common Side Effects
Less Common Side Effects
- Elevated triglycerides or cholesterol
- Mild rash or Pruritus
Serious Side Effects
- Severe liver injury (jaundice, dark urine) - seek medical help immediately.
- Pancreatitis (upper-abdominal pain, vomiting) - contact a health professional.
- Allergic reactions such as swelling of the face or difficulty breathing - call emergency services.
Who Should Avoid This Medication?
- Known hypersensitivity to lopinavir, ritonavir, or any excipients.
- Patients with severe hepatic impairment (Child-Pugh C).
- Concurrent use of strong CYP3A4 inducers that cannot be discontinued.
Storage Instructions
- Keep the bottle at room temperature (15-30 °C), away from direct sunlight.
- Do not store in the bathroom or near heat sources.
- Keep out of reach of children; discard any tablets that are discolored or broken.
Kaletra Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Aluvia (generic) | Protease inhibitor combo | Same active ingredients, lower price |
| Atazanavir + ritonavir | Protease inhibitor (single) | Once-daily dosing but different resistance profile |
| Dolutegravir-based regimens | Integrase inhibitor | Different mechanism, used when protease inhibitors unsuitable |
Frequently Asked Questions
How long does it take for Kaletra to lower HIV viral load?
Typically 4-8 weeks of consistent therapy are needed to see a significant reduction.
Can I take Kaletra with coffee?
Yes, moderate coffee consumption does not affect drug levels, but avoid adding grapefruit juice to any drink.
What if I experience diarrhea?
Stay hydrated, consider a diet low in fatty foods, and discuss with a clinician whether an anti-diarrheal medication is appropriate.
Is it safe to travel abroad while on Kaletra?
Generally yes, but keep tablets in original packaging, carry a copy of the prescription (for reference only), and be aware of any country-specific drug regulations.
Can Kaletra be taken during pregnancy?
It is Category B in Singapore; benefits may outweigh risks, but discuss with your healthcare provider.
Does Kaletra interact with herbal supplements like St. John’s wort?
Yes, St. John’s wort is a strong CYP3A4 inducer and can reduce Kaletra effectiveness-avoid using it together.
What should I do if I miss two consecutive doses?
Contact a healthcare professional promptly; you may need a temporary dosage adjustment.
Are there any dietary restrictions besides grapefruit?
No specific restrictions, but maintain a balanced diet and limit high-fat meals that can affect absorption.
How often should liver function be tested?
Baseline tests before starting, then every 3-6 months or as clinically indicated.
Can I switch from brand Kaletra to a generic version?
Yes, provided the generic is bioequivalent and approved by the Health Sciences Authority.
Glossary
- Protease inhibitor: A class of drugs that block an enzyme HIV needs to replicate.
- Boosted regimen: Using ritonavir to increase the blood level of another drug (lopinavir).
- Bioequivalent: A generic drug that delivers the same amount of active ingredient into the bloodstream as the branded product.
Disclaimer
This handbook provides general information about Kaletra for educational purposes only. It does not replace professional medical advice, and off-label uses are not discussed. Readers are responsible for verifying any information and should consult a qualified health professional before starting or changing therapy. Our online platform offers convenient access to approved medicines in Singapore; all transactions comply with local regulations.
Kaletra Properties
- Original Manufacturer: Abbott Laboratories
- Clinical use: Antiretroviral for HIV treatment, Antiretroviral for HIV treatment
- Spectrum of activity: Narrow-spectrum, Narrow-spectrum
- Mechanism of action: Inhibits HIV protease, Inhibits HIV protease
- Classification: Protease inhibitor, Protease inhibitor
- Recommended Dosage: 400 mg twice daily, 100 mg to 200 mg twice daily
- Basic Side Effects: nausea, diarrhea, fatigue, nausea, diarrhea, fatigue
- Moderate Side Effects: vomiting, abdominal pain, rash, vomiting, abdominal pain, rash
- Serious Side Effects: liver damage, high cholesterol, diabetes, liver damage, high cholesterol, diabetes
Kaletra Connected Conditions
How to purchase Kaletra on our Website
To purchase Kaletra | Lopinavir on our website, just select the required dosage and quantity of pills above. The price of your choice will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more pills or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Kaletra / Lopinavir bottles are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Kaletra bottles are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
First week on Kaletra and it's a nightmare. The diarrhea hit me hard, like 5 times a day. Started taking it with a full meal like they said, but my stomach still feels rough. Doctor warned me it would be tough initially, so I'm trying to stick it out. Hope this gets better soon because it's really draining.
Three months in. The initial nausea and diarrhea finally settled after about a month, thank god. The big issue now is the tingling in my feet and hands - it's weird but manageable. Viral load is undetectable, so it's worth it. Pro tip: take it with peanut butter toast if your stomach is sensitive, helps a lot more than just water.
Been on this for over two years. It keeps my numbers good, but the side effects are stubborn. High cholesterol, have to watch my diet like a hawk. Also, the pills are huge! I've gotten used to it, but it's not exactly fun. Biggest hack: set two phone alarms, one for the pill and one to remind you to grab a snack beforehand.
It's effective, no doubt. But the fat redistribution is real. My face looks thinner but I've got this belly fat that won't shift no matter how much I exercise. It messes with your body image. Other than that, I feel okay. Learned to always carry water because these tablets leave a terrible aftertaste if they start dissolving.
A real love-hate relationship. Undetectable for 5 years thanks to Kaletra, but the digestive issues never fully went away. I have to plan my days around bathroom access. Found that taking a probiotic supplement every morning helps a ton. Also, avoid spicy Thai food too close to dose time, learned that the hard way!
Switched to this combo after failing first-line treatment. It's strong stuff. The fatigue was overwhelming at first, felt like I couldn't get out of bed. After 6 months, energy is better but not great. Lipodystrophy is starting to show. On the plus side, my CD4 count is finally climbing. You trade one set of problems for another, I guess.
Been on Kaletra for 8 years. It's my lifeline, but the long-term metabolic stuff is no joke. Regular blood tests for liver and lipids are a must. The pills themselves are a chore, but I split my dose - one in the morning, one at night with dinner - to lessen the stomach upset. It's a commitment, but it keeps me alive.
Just started last month. The nausea is intense, like morning sickness level. My doctor prescribed something for it which takes the edge off. The weirdest part is the weird metallic taste in my mouth sometimes. Trying to stay hydrated and eat bland foods like porridge. Hoping my body adjusts because right now it's a struggle.