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Generic Ivermectin Buyer and Patient Handbook in Singapore

What is Ivermectin?

Ivermectin is an antiparasitic medication that has also been investigated for antiviral activity. It belongs to the macrocyclic lactone class and is supplied as oral tablets. In Singapore it is approved for treating certain parasitic infections and is available in 3 mg, 6 mg, and 12 mg strengths.

Who Should Use Ivermectin?

• Adults diagnosed with approved parasitic conditions (e.g., Strongyloidiasis, onchocerciasis).
• Patients whose clinicians have determined off-label antiviral use after risk-benefit assessment.
• Individuals without known hypersensitivity to ivermectin or excipients.

How Does It Work?

Ivermectin binds selectively to parasite glutamate-gated chloride channels, increasing chloride ion influx and causing paralysis and death of the organism. For its antiviral investigations, the drug is thought to impair viral protein import into the host nucleus, reducing replication. It does not produce euphoria or dependence, but misuse can lead to neurotoxicity.

Why Choose Ivermectin?

• Generic affordability: identical bioavailability to brand-name versions at a lower cost.
• Well-documented safety profile for approved indications when taken as directed.
• Off-label antiviral applications must be discussed with a qualified health professional.

Dosage, Administration, Lifestyle and Dietary Recommendations

Recommended Dosage

• 3 mg tablet: 1 tablet once daily for 2 days (typical parasitic regimen).
• 6 mg tablet: 1 tablet once daily for 2 days (alternative dosing).
• 12 mg tablet: 1 tablet on day 1, repeat on day 2 (for specific infections).

How to Take

Swallow the tablet whole with a full glass of water; food does not significantly affect absorption, but taking it with a meal may reduce stomach upset.

Missed Dose

If a dose is missed and it is less than 12 hours later, take it as soon as remembered; otherwise skip and resume the regular schedule. Do not double-dose.

Overdose

Seek immediate medical attention if more than the prescribed amount is taken. Supportive care may include activated charcoal and monitoring of neurological status.

Special Populations

• Elderly > 65 years: Start with the lowest effective dose and monitor for dizziness.
• Children < 15 kg: Use only under specialist guidance; dosing is weight-based, not tablet-based.
• Liver impairment: Reduce dose by 50 % and extend dosing interval.

Lifestyle & Diet

Avoid consuming grapefruit or grapefruit juice within 12 hours of the dose, as it can increase plasma concentrations. Alcohol does not interact directly but excess intake may heighten dizziness.

Precautions and Warnings

• Do not use if you have a known allergy to ivermectin or any tablet excipients.
• Contra-indicated in patients with severe liver disease (Child-Pugh C).
• Use caution if you have a history of seizures; neurotoxicity, though rare, can manifest as ataxia or tremor.

Drug Interactions

Potential Side Effects

Common Side Effects

• Nausea
• Diarrhoea
• Dizziness

Less Common Side Effects

• Skin rash
• Mild headache
• Abdominal Pain

Serious Side Effects

• Severe allergic reaction (hives, swelling of face/tongue) - call emergency services
• Neurological signs (confusion, Seizures, loss of consciousness) - seek urgent care

Who Should Avoid This Medication?

• Patients with hypersensitivity to ivermectin or any tablet component.
• Individuals with uncontrolled Epilepsy.
• Pregnant or breastfeeding women, unless benefit outweighs risk after professional consultation.

Storage Instructions

• Keep tablets in the original container, tightly closed.
• Store at 20 °C-25 °C (68 °F-77 °F); protect from excess heat and moisture.
• Keep out of reach of children.

Ivermectin Alternatives

Frequently Asked Questions

How quickly can I expect symptom relief?

Most patients notice improvement within 48 hours for approved parasitic infections; antiviral effects, if any, are not reliably predictable.

Can I take Ivermectin with coffee or tea?

Yes, normal consumption of coffee or tea does not affect absorption.

Is it safe to use Ivermectin while drinking alcohol?

Moderate alcohol intake is not contraindicated, but excessive drinking may worsen dizziness or gastrointestinal upset.

What should I do if I experience a rash?

Stop the medication and contact a health professional; a rash may indicate an allergic reaction.

Can I take Ivermectin while on cholesterol-lowering meds?

Statins are not known to interact with ivermectin; however, always inform your clinician of all current medications.

Does the tablet need to be refrigerated?

No, store at room temperature away from light and moisture.

I missed two consecutive doses; can I still continue?

If more than 24 hours have passed, resume the regular dosing schedule without doubling the next dose.

Are there any foods that block Ivermectin’s effect?

Grapefruit products can increase drug levels; avoid them around dosing times.

How long does a tablet remain effective after opening the blister pack?

Tablets remain stable for up to six months if kept sealed and stored properly.

Is Ivermectin approved for COVID-19 treatment in Singapore?

No; it is not approved for COVID-19, and any off-label use should be discussed with a qualified health professional.

Glossary

• Glutamate-gated chloride channel: A protein that controls chloride ion flow in parasites, leading to paralysis when activated.
• Bioavailability: The proportion of a drug that enters systemic circulation and can have an active effect.
• Off-label: Use of a medication for an indication not formally approved by regulatory agencies.

Disclaimer

The information provided here is for general educational purposes and does not replace professional medical advice. Off-label uses require discussion with a qualified health professional. Our service supplies medicines only after verification of eligibility; we do not provide prescriptions. Always consult a healthcare provider before starting, stopping, or changing any medication.