Buy Zyvox
zyvox
$117.60
- Active ingredient: Linezolid
- Category: Antibiotics
- Delivery time: Airmail (14-21 days) | EMS trackable (5-9 days)
- Prescription: Included
- Availability: In Stock
Zyvox (Linezolid) 600mg tablets are available to purchase from our Singapore pharmacy with reliable delivery. This oxazolidinone antibiotic works by inhibiting bacterial protein synthesis at an early stage, making it effective against drug-resistant organisms like MRSA and VRE. It provides targeted treatment for complicated skin infections, pneumonia, and other serious bacterial conditions. Zyvox is an ideal solution for patients with antibiotic-resistant infections who require advanced pharmacological intervention.
Table of contents
- Zyvox (Linezolid) Buyer and Patient Handbook - Singapore
- What is Zyvox?
- Who Should Use Zyvox?
- How Does It Work?
- Why Choose Zyvox?
- Dosage, Administration, Lifestyle and Dietary Recommendations
- Recommended Dosage
- How to Take
- Missed Dose
- Overdose
- Special Populations
- Lifestyle & Diet
- Precautions and Warnings
- Drug Interactions
- Potential Side Effects
- Common Side Effects
- Less Common Side Effects
- Serious Side Effects
- Who Should Avoid This Medication?
- Storage Instructions
- Zyvox Alternatives
- Frequently Asked Questions
- How quickly will I feel better after starting Zyvox?
- Can I drink coffee while taking Zyvox?
- Is it safe to take Zyvox with my antihypertensive medication?
- What should I do if I develop a rash?
- Does Zyvox interact with herbal supplements?
- Can I take Zyvox while on a low-protein diet?
- Will I need blood tests during treatment?
- Is Zyvox safe for people with diabetes?
- How long is the typical treatment duration?
- What happens if I miss several doses in a row?
- Glossary
- Disclaimer
- Zyvox Drug Class
- Zyvox Connected Conditions
- How to order Zyvox from our Pharmacy
- Reviews
- Write your review
Zyvox (Linezolid) Buyer and Patient Handbook - Singapore
What is Zyvox?
Zyvox is a synthetic antibiotic belonging to the oxazolidinone class, used to treat serious bacterial infections caused by Gram-positive organisms. It is approved for conditions such as complicated skin and soft-tissue infections and community-acquired or hospital-acquired Pneumonia. Zyvox has received regulatory clearance from the Health Sciences Authority (HSA) in Singapore and is supplied as a 600 mg oral tablet.
Who Should Use Zyvox?
- Adults with confirmed or highly suspected infections caused by Staphylococcus aureus (including MRSA) or Streptococcus pneumoniae that are susceptible to linezolid.
- Patients who cannot tolerate β-lactam antibiotics or have Allergies to penicillins or cephalosporins.
- Individuals requiring an oral option after an initial intravenous course of linezolid.
How Does It Work?
Zyvox inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing the formation of a functional initiation complex. Think of it as putting a brake on the bacterial “factory line,” stopping the production of essential proteins and halting growth. This mechanism is bacteriostatic for most strains but can be bactericidal at higher concentrations. Abuse potential is low, but prolonged use can suppress bone-marrow function, so monitoring is advised.
Why Choose Zyvox?
- Rapid oral bioavailability (≈100 %) eliminates the need for prolonged IV therapy.
- Broad activity against MRSA and VRE makes it a reliable option when first-line agents fail.
- The branded formulation offers consistent tablet hardness and dissolution profiles; generic linezolid products are available and are therapeutically equivalent.
- Off-label uses (e.g., multidrug-resistant tuberculosis) should only be considered after specialist advice.
Dosage, Administration, Lifestyle and Dietary Recommendations
Recommended Dosage
- 600 mg once daily for adults.
- For specific severe infections, a loading dose of 600 mg every 12 hours for the first 24 hours may be prescribed, followed by daily dosing.
How to Take
- Swallow the tablet whole with a glass of water.
- Can be taken with or without food; however, a light meal may reduce mild gastrointestinal discomfort.
Missed Dose
- If you remember the missed dose within 12 hours, take it immediately.
- If more than 12 hours have passed, skip the missed dose and resume your regular schedule. Do not double-dose.
Overdose
- Contact emergency services or the nearest hospital if you suspect an overdose.
- Overdose symptoms may include dizziness, Nausea, and severe headache; supportive care will be provided.
Special Populations
- Elderly: No dose adjustment needed, but monitor blood counts closely.
- Renal impairment: No adjustment for mild-to-moderate impairment; severe impairment (creatinine clearance <30 mL/min) may require dose reduction.
- Hepatic impairment: Use with caution; monitor liver enzymes.
- Pregnancy & lactation: Use only if the benefit outweighs the risk; linezolid passes into breast milk.
Lifestyle & Diet
- Avoid excessive alcohol as both can increase the risk of Peripheral Neuropathy.
- Grapefruit juice does not affect linezolid metabolism, but maintain a balanced diet to support overall health.
- Inform your pharmacist if you are using tyramine-rich foods (e.g., aged cheese) while on monoamine-oxidase inhibitors, as a rare drug interaction exists.
Precautions and Warnings
- Myelosuppression: Weekly complete blood counts are recommended for treatments >2 weeks.
- Peripheral and optic neuropathy: Report numbness, vision changes, or tingling immediately.
- Serotonin syndrome risk: Concurrent use with serotonergic agents (SSRIs, SNRIs, TCAs, MAOIs, linezolid’s weak MAO inhibition) can precipitate life-threatening symptoms.
- Drug-induced liver injury: Monitor hepatic function if pre-existing liver disease exists.
Drug Interactions
| Interacting Drug Class | Risk | Action |
|---|---|---|
| SSRIs / SNRIs | ↑Serotonin syndrome | Avoid combo or monitor closely |
| MAO inhibitors | ↑Serotonin syndrome | Contraindicated |
| Rifampicin | ↓Linezolid levels | Increase monitoring or adjust dose |
Potential Side Effects
Common Side Effects
Less Common Side Effects
Serious Side Effects
- Severe neutropenia or thrombocytopenia - seek urgent medical care.
- Peripheral neuropathy (numbness, tingling) - stop medication and consult a physician.
- Optic neuropathy (blurred vision, color changes) - discontinue and obtain ophthalmologic assessment.
Who Should Avoid This Medication?
- Patients with known hypersensitivity to linezolid or any component of the tablet.
- Individuals currently on MAO inhibitors (unless the inhibitor has been stopped ≥14 days).
- Patients with pre-existing severe bone-marrow suppression unless benefits clearly outweigh risks.
Storage Instructions
- Keep tablets in the original container, tightly closed.
- Store at 20-25 °C (68-77 °F), protected from moisture and light.
- Keep out of reach of children and pets.
Zyvox Alternatives
| Name | Class | Key Difference |
|---|---|---|
| Generic linezolid | Oxazolidinone | Lower cost, same efficacy |
| Vancomycin (IV) | Glycopeptide | Requires infusion, renal monitoring |
| Daptomycin | Lipopeptide | Not for pneumonia, muscle toxicity risk |
Frequently Asked Questions
How quickly will I feel better after starting Zyvox?
Most patients notice improvement in symptoms within 2-3 days, but complete eradication of infection may take 7-14 days of therapy.
Can I drink coffee while taking Zyvox?
Yes, moderate coffee intake does not affect linezolid’s effectiveness.
Is it safe to take Zyvox with my antihypertensive medication?
Generally safe, but inform your clinician of all current drugs; monitor blood pressure as usual.
What should I do if I develop a rash?
Stop the medication and seek medical advice promptly; a mild rash may resolve, but severe reactions require urgent care.
Does Zyvox interact with herbal supplements?
Certain supplements that affect serotonin (e.g., St. John’s wort) could increase serotonin syndrome risk; discuss any herbal use with your pharmacist.
Can I take Zyvox while on a low-protein diet?
Yes, dietary protein does not influence linezolid absorption.
Will I need blood tests during treatment?
Weekly complete blood counts are recommended for courses longer than 2 weeks to detect early myelosuppression.
Is Zyvox safe for people with diabetes?
Linezolid does not affect glucose metabolism, but monitor blood sugar as usual; infection itself can cause fluctuations.
How long is the typical treatment duration?
Standard courses range from 10 to 14 days, depending on infection severity and clinical response.
What happens if I miss several doses in a row?
Contact your healthcare provider to reassess treatment; missing multiple doses may reduce efficacy and increase resistance risk.
Glossary
- Oxazolidinone: A class of antibiotics that block bacterial protein synthesis at the ribosomal level.
- Serotonin syndrome: A potentially life-threatening condition caused by excess serotonergic activity, presenting with Agitation, hyperthermia, and neuromuscular abnormalities.
- Myelosuppression: Reduced production of blood cells by the bone marrow, leading to anemia, infection risk, or bleeding.
Disclaimer
The information provided here is for educational purposes only and reflects current knowledge as of the publication date. It does not replace professional medical advice. Off-label use should be discussed with a qualified healthcare professional. Our online pharmacy platform offers information on medication availability and pricing in Singapore, but the ultimate responsibility for safe use lies with the patient and their clinician. Always consult a doctor or pharmacist before starting, stopping, or altering any medication.
Zyvox Drug Class
Zyvox Connected Conditions
How to order Zyvox from our Pharmacy
To order Zyvox | Linezolid on our online pharmacy, all you need to do is select the required dosage and quantity of pills above. The cost of the selected pack will appear automatically. Next, add the chosen amount to your cart by clicking the Add to Cart button. You can either continue shopping for more medications or head to the checkout. At the Checkout, finalize your purchase through our secure payment gateway.
Zyvox / Linezolid pills are made using high-quality generic ingredients and are subject to strict quality control in line with WHO and Health Sciences Authority (HSA) standards. However, please note that Zyvox pills are dispatched from outside Singapore due to prescriptions issued overseas.
Disclaimer: The content on this website is provided solely for informational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions or concerns regarding your health, and never disregard or delay seeking professional advice based on the information presented here. Use of this website does not create a doctor-patient relationship, and in the event of a medical emergency, please contact your local emergency services immediately. Our website assumes no responsibility or liability for any errors or omissions in the content provided.
Reviews
Zyvox saved my foot from MRSA, no exaggeration. But guys, the nausea the first three days was brutal. Major tip: ONLY take the 600mg pill right after a huge meal, like seriously heavy lunch. If you try to take it on an empty stomach, you will regret it. Also, the taste when it dissolves even slightly in your mouth? Pure metallic horror. Swallow it fast. The energy crash hits around 3 PM for me, so I try to schedule my life around that post-dose energy dip. Totally worth it, though, if you have a resistant infection.
Just started day two on this 600mg beast for a lung infection. The headache is continuous, like a tight band around my forehead. My doctor warned me about the serotonin stuff, so I'm super careful about what I eat. Had some mild brain zaps this morning when I moved too fast? Did anyone else get that? Scared to finish the full 14 days, but the infection count is finally dropping. Need advice on managing the jitteriness; feels like I drank ten espresso shots, but I'm exhausted.
I've been on and off Zyvox (Linezolid 600mg) for years for chronic osteomyelitis flare-ups. The blood work checks are constant, especially the platelet count-don't ignore those. Biggest user hack: always take a B6 supplement (around 50mg) every day. This dramatically reduced the peripheral neuropathy (tingling in fingers and toes) that started happening after the second round. Yes, it kills the bad bugs, but it also strips your system. It's a necessary evil, but you need to be proactive.
This drug is a nightmare for sleep. Absolute torture. I take the 600mg dose in the morning now because if I take it past 2 PM, I'm staring at the ceiling until 4 AM. It works wonders on the pneumonia that nothing else touched, but I feel like a zombie all day. Pro tip for the taste: immediately chase it with something sour, like a sip of lime juice or tamarind candy. It cancels the bitter metallic edge instantly. My vision is also slightly blurry, which is concerning after six weeks, but my consultant says it's reversible.
Started Zyvox for Vancomycin-Resistant Enterococcus (VRE) and it knocked it out faster than I expected. That's the good part. The bad part is the GI upset is relentless. I mean cramping, bloating, the works. I tried splitting the 600mg dose into 300mg morning and 300mg evening, and honestly, that helped settle my stomach significantly without affecting the efficacy. It still gives me weird, vivid dreams when I take the second half, though. Also avoid fermented foods-trust me on this, serious headache territory.
Mixed feelings. It cleared up a persistent skin infection that was bothering me for three months. Great! But my mood plummeted. Like, suddenly I felt intensely irritable and anxious for no reason. I wasn't on any other antidepressants, so I know it was the Linezolid messing with my serotonin. This lasted for about five days after I finished the course. Be ready for the emotional rollercoaster. It works as an antibiotic, just wish the nervous system side effects weren't so dramatic.
I'm a few weeks in, 600mg twice daily. My primary concern is the dizziness/vertigo. Moving too fast makes me feel like I'm on a boat. It makes driving impossible, so plan for downtime if you take this. I learned the hard way: NO ALCOHOL. I had one small glass of red wine and felt completely spaced out, almost hallucinatory. The infection is gone, thank goodness, but this medication really demands full lifestyle compliance. You can't cheat the rules while on Zyvox.
The worst side effect? Elevated blood pressure. My heart felt like it was racing all the time, especially in the first week. If you have any underlying heart issues, be extremely cautious. My advice: check your blood pressure at home twice a day while on the 600mg dose. User hack: Drink plenty of water and electrolytes, and maybe cut the caffeine completely for the first week to manage the nervous system hyper-stimulation. It did successfully treat my bone infection, but the recovery from the side effects took another week itself.